ACE Technology Guidances communicate recommendations from the MOH Drug Advisory Committee or the MOH Medical Technology Advisory Committee on the funding status and appropriate use of drugs, vaccines or medical technologies that have been evaluated by ACE. The guidances also include the Committee’s rationale for the funding recommendations, and key clinical and economic evidence which informed their deliberations. Plain English Summaries (PES) to explain ACE Technology Guidances are available for patients and the public.

Published on 31 Aug 2022
Last Updated on 02 Jan 2024
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Guidance Recommendations

The Ministry of Health’s Drug Advisory Committee has not recommended cabozantinib in combination with nivolumab for inclusion on the MOH List of Subsidised Drugs for previously untreated advanced renal cell cancer in view of unfavourable cost-effectiveness compared with alternative treatments.

Clinical indications, subsidy class and MediShield Life claim limits for both drugs are provided in the Annex.


Cabozantinib with nivolumab for previously untreated advanced RCC (Updated 1 Aug 2023) PES Treatments for advanced renal cell carcinoma (Updated 2 Jan 2024)